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KMID : 0381919980280020215
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Korean Journal of Microscopy
1998 Volume.28 No. 2 p.215 ~ p.224
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Ultrastructural Studies on the Adrenal Medulla of The Developmental Rats
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Park Joo-Hee
Lee Jae-Hyun
Ku Sae-Kwang
Lee Hyeung-Sik
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Abstract
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To investigate ultrastructural changes on the adrenal glands of the developmental rats, tissues were collected at 20 days of gestation, at birth, 7 days, 15 days and 30 days after birth and studied by electron microscope. In the medulla of adrenal gland of the rat, two types of granules were observed at ultrastructural level. The one were adrenaline $(123\sim200nm)$ and the others were noradrenaline ($177\sim279nm$ of long axis, $124\sim194$ of short axis). Adrenaline granules were characterized by presence of round or spherical with low or moderate electron density. The granules showed a wide lucent or clean halo between the contents and the limiting membrane. On the other hand noradrenaline granules were characterized by the presence of irregular shape with high electron density. This granules showed a wide lucent between the contents and limiting membrane. These two types of granules were co-existed in one cell in the late gestation and at birth, but after that two types of cells were clearly observed. The different sizes and numbers of granules were observed with ages.
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KEYWORD
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Rat, Age, Adrenal medulla, Granules
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